Research Technologist – Cell Therapy Manufacturing (GMP) Job Listing at Roswell Park Comprehensive Cancer Center in Buffalo, NY (Job ID R-19458)

Description

Title: Research Technologist – Cell Therapy Manufacturing (GMP)

Job Type:

Regular Company: Health Research, Inc. (HRI) Roswell Park Division Department: Center for Immunotherapy Time Type: Full time Weekly Hours: 40

FTE:

1 Shift: First Shift (United States of America) Summary: Join a mission-driven team at the forefront of cutting-edge cell and gene therapies. At Roswell Park's state-of-the-art GMP Engineering & Cell Manufacturing (GEM) Facility, we are pioneering advanced immunotherapies like CAR-T with the goal of transforming patient care.

We are seeking a Research Technologist to play a key role in the clinical manufacturing of cell therapy products. This is a hands-on, lab-based position within a dynamic cGMP environment, ideally suited for individuals passionate about cellular therapeutics and high-impact translational research. The pay range for the Research Technologist position is $50,456 - $63,986 annually which includes a comprehensive benefits package. The listed pay range reflects the range of potential compensation for this role. The actual offer may vary based on qualifications, skills, and experience

Key Responsibilities:

• Execute end-to-end cell manufacturing processes under cGMP conditions to produce clinical-grade CAR-T and other advanced therapy products.
• Collaborate cross-functionally with Manufacturing Sciences, Process Development, and Quality Assurance teams to ensure seamless technology transfer, facility fit assessments, and process risk evaluations.
• Contribute to continuous improvement initiatives to optimize processes and ensure readiness for clinical trial demands and regulatory audits.
• Maintain accurate, real-time documentation to uphold data integrity and traceability in line with cGMP and institutional requirements.

What You'll Bring:

• A strong foundation in cell culture and aseptic technique, ideally in a cGMP or regulated environment.
• A detail-oriented mindset with a commitment to quality and operational excellence.
• Effective communication and teamwork skills to support cross-departmental projects.
• Adaptability and drive to work in a fast-paced, evolving field at the intersection of science and medicine.

Why Roswell Park?

• Be part of a nationally recognized cancer center with a legacy of innovation and patient-centered care.
• Access to world-class facilities, resources, and training to support your professional growth.
• The opportunity to directly contribute to life-saving therapies that make a difference in patients' lives. Qualifications: Required Education and Experience

1. Master's degree in a clinical or scientific discipline; or
2. Bachelor's degree in a clinical or scientific discipline and the equivalent of one (1) year of full-time experience in a laboratory setting.

NOTE:
Required degrees must have been granted by an accredited school, college or university or one recognized by Roswell Park Comprehensive Cancer Center as following acceptable educational practices.

Preferred Qualifications:

The preferred candidate will have:

• Extensive hands-on expertise in T-cell engineering—including molecular biology techniques and execution of complex analytical assays—to support advanced cell therapy development.
• Demonstrated proficiency in cellular assays, such as flow cytometry, cytotoxicity, and viability testing, with a strong analytical mindset and troubleshooting capabilities.
• Working knowledge of cGMP standards, including experience with production documentation, batch records, and compliance-driven environments.
• Solid foundation in aseptic technique and mammalian cell culture, with a track record of maintaining sterility and culture integrity in high-throughput or regulated settings.
• Strong communication skills, with the ability to convey scientific concepts clearly across cross-functional teams; collaborative, articulate, and committed to scientific excellence.
• Hands-on experience in cell therapy—such as CAR-T, stem cell-based platforms, or other adaptive cell transfer modalities—spanning research, process development, or manufacturing.
• Familiarity with key tools and systems used in clinical and commercial cell therapy production, including CliniMACS Plus/Prodigy, Cocoon, or comparable platforms.
• Exceptional attention to detail, especially in documentation, cleanliness, and organization—critical qualities for maintaining reproducibility and regulatory compliance.

Equal Employment Opportunity Statement

Roswell Park Cancer Institute Corporation (RPCIC) and Health Research Inc. (HRI) Roswell Park Division believe that all persons are entitled to equal employment opportunities, and we do not discriminate against our employees, applicants or job seekers because of their race, color, religion, sex, sexual orientation, gender identity or expression, national origin, creed, age, disability, pregnancy-related condition, military or veteran status, marital or familial status, domestic violence victim status, citizenship status, genetic information, individual's relationship or association with a member of a protected category or any other protected group status as defined by law.

Affirmative Action/Equal Opportunity Employer/Qualified Individuals with Disabilities/Qualified Protected Veterans

Reasonable Accommodation Request

RPCIC and HRI are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the employment process, please email HR-PayAndBenefits@RoswellPark.org  and let us know the nature of your request and your contact information.

Our Core Values

RPCIC and HRI are committed to providing an environment where patients, families, employees and community are treated with courtesy and respect. We support an inclusive environment that nurtures the talents, skills and abilities of each individual to embody and reflect our core values: Innovation, Integrity, Teamwork, Commitment, Compassion and Respect.

Grant Funding

This is a grant-funded position.  Compliance with funding requirements such as time and effort reporting, grant deliverables, and contract deliverables is required.

E-Verify Employer

Health Research Inc. (HRI) Roswell Park Division participates in the E-Verify program.

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