Frederick National Laboratory Job - 32411409 | CareerArc
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Company: Frederick National Laboratory
Location: Frederick, MD
Career Level: Entry Level
Industries: Healthcare, Pharmaceutical, Biotech


Scientist I, R&D

Job ID: req1188
Employee Type: exempt full-time
Facility: Frederick: ATRF
Location: 8560 Progress Dr, Frederick, MD 21701 USA

The Frederick National Laboratory is a Federally Funded Research and Development Center (FFRDC) sponsored by the National Cancer Institute (NCI) and operated by Leidos Biomedical Research, Inc.  The lab addresses some of the most urgent and intractable problems in the biomedical sciences in cancer and AIDS, drug development and first-in-human clinical trials, applications of nanotechnology in medicine, and rapid response to emerging threats of infectious diseases.

Our core values of accountability, compassion, collaboration, dedication, integrity, and versatility serve as a guidepost for how we do our work every day in serving the public's interest.  

 Position Overview:


At the Frederick National Laboratory, the Cancer Research Technology Program (CRTP) is an outward-facing, multi-disciplinary hub where emerging technologies, cancer biology expertise and research capabilities are developed and implemented in a collaborative manner to accomplish NCI research objectives. Within the CRTP is the Center for Molecular Microscopy (CMM), a laboratory where cutting-edge electron microscopy (EM) is applied to reconstruct protein structures and cellular architectures in 3-D and high resolution. In our group, scientists work in a collaborative environment to develop and deploy new technologies for high-resolution 3-D volume EM of cells and tissues with research and/or clinical relevance. Our group works on innovations in sample preparation, imaging strategies, image processing and data analysis.


  • Overseeing and operating the fluorescence microscopy and cryo prep components of the laboratory
  • Operation of tissue culture facilities as needed
  • Shared execution of EM sample preparation and QC steps
  • Management of laboratory inventories
  • Opportunity to lead, write up and publish on specific projects
  • Work and communicate well in a team-oriented environment to carry out technological development and collaborative efforts.


  • Possession of a Doctoral degree in biological sciences or related scientific field from an accredited university according to the Council for Higher Education Accreditation. Foreign degrees must be evaluated for U.S. equivalency
  • Experience in fluorescence microscopy and/ or electron microscopy: sample preparation, microscope operation, basic image analysis and visualization
  • Tissue culture and cell handling experience
  • Peer-reviewed publications with full or significant contribution to writing of manuscript
  • Must be able to obtain and maintain a security clearance


  • Experience with 3-D EM techniques (FIB-SEM, SBF-SEM etc)
  • Experience with cryo workflows
  • Experience in lab management


  • This position is subject to working with or have potential for exposure to infectious material, requiring medical clearance and immunizations
  • This position is subject to working with radioactive material and requires to become an approved radiation worker

Equal Opportunity Employer (EOE) | Minority/Female/Disabled/Veteran (M/F/D/V) | Drug Free Workplace (DFW)


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